| Date | Game Date | Player | Position | Age | Transaction Type |
|---|---|---|---|---|---|
| 05/21/22 | March 16th 2055 | Ignacio Lezcano | C | 18 | Latin American Academy Signee |
| 05/21/22 | March 16th 2055 | Miguel Heredia | 2B | 20 | Waiver Claim [1 claims] |
| 05/15/22 | March 4th 2055 | Rodney Fultz | P | 29 | Released |
| 05/15/22 | March 4th 2055 | Tom Hansen | P | 23 | Released |
| 05/15/22 | March 4th 2055 | Anthony Steffen | OF | 29 | Free Agent Signee |
| 05/13/22 | February 19th 2055 | Martín Orosco | OF | 31 | Released |
| 05/13/22 | February 19th 2055 | Luis Nava | SS | 26 | Released |
| 05/13/22 | February 19th 2055 | Robbie Rueter | OF | 31 | Released |
| 05/13/22 | February 19th 2055 | Robbie Rueter | OF | 31 | Waiver Claim [1 claims] |
| 05/12/22 | February 5th 2055 | Esteban Lira | OF | 31 | Waiver Claim [7 claims] |
| 05/10/22 | January 13th 2055 | Alfredo Guerrero | 1B | 31 | Free Agent Signee |
| 05/10/22 | January 13th 2055 | Martín Orosco | OF | 31 | Free Agent Signee |
| 05/07/22 | January 13th 2055 | Daniel Ordonez | 1B | 31 | Released |
| 05/07/22 | January 13th 2055 | Roger Boyle | 1B | 22 | Released |
| 05/07/22 | January 13th 2055 | Alberto Escobar | C | 34 | Released |
| 05/07/22 | January 13th 2055 | Yasmany Tamayo | OF | 33 | Released |
| 05/07/22 | January 13th 2055 | Elvis Kiefer | OF | 33 | Released |
| 04/05/22 | July 9th 2054 | José Benavides | 1B | 18 | Waiver Claim [2 claims] |
| 04/02/22 | June 27th 2054 | Peter Hiatt | 2B | 19 | Free Agent Signee |
| 04/01/22 | June 25th 2054 | Santiago Abreu | C | 16 | Released |
| 04/01/22 | June 25th 2054 | Jesús Carrasco | P | 20 | Released |
| 04/01/22 | June 25th 2054 | Santiago Abreu | C | 16 | Latin American Academy Signee |
| 03/25/22 | May 29th 2054 | Jesús Carrasco | P | 20 | Latin American Academy Signee |
| 03/23/22 | May 21st 2054 | Fabián Silinas | 2B | 17 | Released |
| 03/18/22 | May 3rd 2054 | Fabián Silinas | 2B | 17 | Latin American Academy Signee |