| Date | Game Date | Player | Position | Age | Transaction Type |
|---|---|---|---|---|---|
| 08/01/21 | May 10th 2051 | Ramiro Espinoza | P | 17 | Released |
| 08/01/21 | May 10th 2051 | Ramiro Espinoza | P | 17 | High School Draftee |
| 07/06/21 | January 19th 2051 | Corey Graves | P | 22 | Released |
| 07/06/21 | January 19th 2051 | Ben Wikstrom | OF | 25 | Released |
| 07/06/21 | January 19th 2051 | Felix Valencia | P | 37 | Released |
| 07/06/21 | January 19th 2051 | Lázaro Suárez | P | 37 | Released |
| 06/05/21 | July 28th 2050 | Joe Reardon | OF | 23 | Released |
| 06/06/21 | July 28th 2050 | Blair Pruitt | P | 17 | High School Draftee |
| 06/05/21 | July 28th 2050 | Mateo Santiago | 2B | 35 | Released |
| 05/21/21 | May 29th 2050 | Wally Bach | OF | 17 | High School Draftee |
| 05/16/21 | May 10th 2050 | Rafael Best | OF | 17 | High School Draftee |
| 05/07/21 | April 7th 2050 | Wesley Wojcik | SS | 17 | High School Draftee |
| 05/03/21 | March 20th 2050 | Gary Hornsby | P | 17 | High School Draftee |
| 04/02/21 | September 13th 2049 | Craig Webb | P | 17 | Released |
| 04/02/21 | September 13th 2049 | Craig Webb | P | 17 | High School Draftee |
| 03/27/21 | August 25th 2049 | Rob Harris | P | 22 | Released |
| 03/27/21 | August 25th 2049 | Diego Rios | P | 21 | Released |
| 03/28/21 | August 25th 2049 | Diego Rios | P | 21 | Latin American Academy Signee |
| 03/22/21 | August 2nd 2049 | Mason Calhoun | C | 17 | Released |
| 03/22/21 | August 2nd 2049 | Mason Calhoun | C | 17 | High School Draftee |
| 03/12/21 | June 25th 2049 | Lee Mundy | 1B | 17 | Released |
| 03/12/21 | June 25th 2049 | Lee Mundy | 1B | 17 | High School Draftee |
| 03/05/21 | May 29th 2049 | Tyreke Daniel | 2B | 17 | High School Draftee |
| 03/04/21 | May 25th 2049 | Jody Kaplan | P | 17 | High School Draftee |
| 02/24/21 | April 25th 2049 | Jonathon Rains | P | 17 | Released |