| Draft Selection | Draft Source | Position | Player | Age | SI | Pot | Assignment | Team | Statistics | |
|---|---|---|---|---|---|---|---|---|---|---|
| 2067, Rd #3 | Latin American Academy | P | Rueben Quiroz | 19 | 54 → 56 | 12 → 11 | Rookie | League City Indians | ||
| 2067, Rd #2 | High School | 1B | Brent New | 18 | 56 → 59 | 11 | Rookie | League City Indians | ||
| 2067, Rd #1 | College | SS | Lou Hines | 21 | 84 → 92 | 15 | AAA | League City Indians | ||
| 2066, Rd #8 | Latin American Academy | 3B | Mateo Zelaya | 22 | 65 → 70 | 10 | AA | League City Indians | ||
| 2066, Rd #6 | College | P | Cesar Saenez | 22 | 51 → 64 | 12 → 11 | AAA | League City Indians | ||
| 2066, Rd #4 | College | P | Patrick Costa | 22 | 65 → 76 | 11 → 10 | AAA | League City Indians | ||
| 2066, Rd #3 | Latin American Academy | 2B | Pedro Arce | 22 | 84 → 88 | 12 → 11 | AAA | League City Indians | ||
| 2066, Rd #2 | Junior College | 2B | Ruben Birch | 20 | 74 → 83 | 13 → 12 | AA | League City Indians | ||
| 2066, Rd #1 | Junior College | OF | Jonathan Dudley | 20 | 66 → 75 | 14 → 13 | AA | League City Indians | ||
| 2065, Rd #7 | College | 3B | Neal Schuler | 23 | 63 → 82 | 12 | AAA | League City Indians | ||
| 2065, Rd #6 | Latin American Academy | OF | Víctor Araujo | 19 | 72 → 79 | 11 → 12 | A | League City Indians | ||
| 2065, Rd #5 | Latin American Academy | OF | Chico Rodrígues | 21 | 69 → 72 | 9 | - | - | ||
| 2065, Rd #4 | College | OF | Russell Pemberton | 23 | 73 → 85 | 12 → 11 | AAA | League City Indians | ||
| 2065, Rd #3 | Latin American Academy | P | René Sandoval | 22 | 48 → 70 | 10 | Majors | League City Indians | G 80, W 5, L 2, ERA 6.16, IP 61⅓, K 30 | |
| 2065, Rd #2 | College | 2B | Jon Arndt | 24 | 75 → 98 | 15 | Majors | League City Indians | G 75, AVE .250, H 12, HR 2, R 18, RBI 9, SB 5 | |
| 2065, Rd #1 | College | P | Randall East | 23 | 43 → 66 | 11 → 10 | Majors | League City Indians | ||
| 2064, Rd #8 | Latin American Academy | 2B | Rodrigo Ledesma | 24 | 63 | 10 → 11 | - | - | ||
| 2064, Rd #7 | High School | 3B | Ruben Coble | 21 | 58 → 69 | 10 → 11 | AA | League City Indians | ||
| 2064, Rd #6 | Latin American Academy | P | Fernando Báez | 24 | 53 → 72 | 10 | AAA | League City Indians | ||
| 2064, Rd #5 | High School | P | Ken Byrnes | 21 | 51 → 65 | 9 | - | - | ||
| 2064, Rd #4 | Latin American Academy | C | Jorge García | 20 | 80 → 88 | 11 | AA | League City Indians | ||
| 2064, Rd #3 | Latin American Academy | 1B | Rubén Solorzano | 23 | 65 → 71 | 8 → 9 | - | - | ||
| 2064, Rd #2 | Junior College | C | Johnny Hayes | 23 | 87 → 109 | 15 → 14 | Majors | League City Indians | G 195, AVE .223, H 109, HR 9, R 64, RBI 55, SB 19 | |
| 2064, Rd #1 | High School | P | Sammie Roberts | 21 | 35 → 54 | 12 → 11 | AA | League City Indians | ||
| 2063, Rd #4 | International | P | Kyle May | 25 | 34 → 39 | 11 | - | - | ||