| Draft Selection | Draft Source | Position | Player | Age | SI | Pot | Assignment | Team | Statistics | |
|---|---|---|---|---|---|---|---|---|---|---|
| 2069, Rd #5 | College | 3B | Omar Arevalo | 21 | 62 | 11 | - | - | ||
| 2069, Rd #4 | College | OF | Ian Underwood | 21 | 79 → 81 | 12 | AA | East St. Louis Cardinals | ||
| 2069, Rd #3 | College | P | Bryce Giles | 21 | 49 | 11 | Rookie | East St. Louis Cardinals | ||
| 2069, Rd #2 | Latin American Academy | P | Pascual Arevalo | 22 | 49 | 13 → 12 | Rookie | East St. Louis Cardinals | ||
| 2069, Rd #1 | Asian Posting System | P | Hiromichi Tachibana | 27 | 74 → 86 | 13 | Majors | East St. Louis Cardinals | G 33, W 7, L 4, S 1, ERA 3.78, IP 69 , K 30 | |
| 2068, Rd #8 | Latin American Academy | 1B | Manuel Arellano | 19 | 57 → 60 | 11 | Rookie | East St. Louis Cardinals | ||
| 2068, Rd #7 | Latin American Academy | 3B | Marco Duran | 21 | 67 → 72 | 11 | AA | East St. Louis Cardinals | ||
| 2068, Rd #6 | High School | OF | Lane Echols | 19 | 47 | 10 → 9 | - | - | ||
| 2068, Rd #5 | Latin American Academy | P | Marcelo Acevedo | 21 | 41 | 10 | - | - | ||
| 2068, Rd #4 | Latin American Academy | SS | Pedro Flores | 21 | 66 → 78 | 12 | AAA | East St. Louis Cardinals | ||
| 2068, Rd #3 | Asian Posting System | P | Hendri Jayadi | 28 | 76 | 12 | - | - | ||
| 2068, Rd #2 | College | OF | Stacy Finney | 22 | 59 → 69 | 12 | AAA | East St. Louis Cardinals | ||
| 2068, Rd #1 | College | P | Harold Friedrich | 22 | 55 → 58 | 13 → 12 | Rookie | East St. Louis Cardinals | ||
| 2067, Rd #7 | High School | OF | Mauricio Madrigal | 20 | 69 → 73 | 10 → 11 | A | East St. Louis Cardinals | ||
| 2067, Rd #6 | College | OF | Logan Kiser | 23 | 81 → 91 | 12 | AAA | East St. Louis Cardinals | ||
| 2067, Rd #5 | High School | P | Rich Mears | 20 | 39 → 49 | 10 → 11 | Rookie | East St. Louis Cardinals | ||
| 2067, Rd #4 | High School | 1B | Reginald Jones | 20 | 51 → 63 | 11 | AA | East St. Louis Cardinals | ||
| 2067, Rd #3 | High School | OF | Cade Gregori | 20 | 64 → 72 | 14 → 13 | AA | East St. Louis Cardinals | ||
| 2067, Rd #2 | Junior College | P | Ralph Parrish | 21 | 40 → 57 | 13 | A | East St. Louis Cardinals | ||
| 2067, Rd #1 | High School | P | Antonio Meza | 20 | 49 → 67 | 15 | A | East St. Louis Cardinals | ||
| 2066, Rd #8 | Latin American Academy | OF | Mateo Ordoñez | 21 | 61 | 9 | - | - | ||
| 2066, Rd #5 | Latin American Academy | OF | Caesar Hurtado | 25 | 72 → 78 | 11 | - | - | ||
| 2066, Rd #4 | Latin American Academy | OF | Iván Marte | 20 | 63 → 73 | 12 → 13 | AA | East St. Louis Cardinals | ||
| 2066, Rd #3 | College | OF | Logan Clancy | 24 | 74 → 93 | 12 | Majors | East St. Louis Cardinals | G 71, AVE .239, H 47, HR 4, R 22, RBI 19 | |
| 2066, Rd #2 | Latin American Academy | C | Ramon Espinosa | 22 | 54 | 11 → 10 | - | - | ||